Friday, July 13, 2012

TRAMADOL



Indications:
TRAMADOL is indicated for treating and preventing moderate to severe pain, such as those below:

  • Acute and chronic pain is severe.
  • Pain after surgery.


Contra Indications:

  • Acute poisoning by alcohol, hypnotics, analgesics or medications that affect other CNS.
  • Patients receiving monoamine oxidase inhibitor treatment (MAO).
  • Patients who are hypersensitive to tramadol.


Composition:

  • Each capsule contains:
  • Tramadol Hydrochloride 50 mg .....................................


How Drugs Work:


  • TRAMADOL is a powerful analgesic that works on opiate receptors.
  • Stereospsifik tramadol binds to receptors in the central nervous system to stop the sensation of pain and response to pain. In addition tramadol inhibits the release of neutrotransmiter of afferent nerves that are sensitive to stimuli, resulting in stunted pain impulses.

Side Effects:
  • Same as generally centrally acting analgesics, side effects may occur: nausea, vomiting, dyspepsia, obstipasi, fatigue, sedation, dizziness, pruritus, sweating, flushed skin, dry mouth and headache.
  • Although tramadol interact with receptors apiat until now proven incidence after the use of tramadol addiction, lightweight.


Attention:

  • Be careful when used in patients with head trauma, increased intracranial pressure, impaired kidney and liver function are severe or bronchial hypersecretion; because it can increase the risk of seizures or shock.
  • Can a decline in lung function when the use of tramadol in combination with drugs or other CNS depression when exceeding the recommended dosage.
  • Tramadol should not be used in patients with drug dependence. Although including opiate agonist, tramadol can not suppress withdrawal symptoms, due to administration of morphine.
  • Tramadol should not be given to pregnant women unless absolutely necessary.
  • 0.1% of tramadol is excreted through breast milk (breast milk).
  • TRAMADOL sufferers can reduce the rate of reaction, such as the ability to drive or operate machinery.
  • Duration of treatment
  • In the long-term treatment, the possibility of dependence, therefore the doctor must set the length of treatment. Should not be given for longer than is necessary.


Drug Interactions:

  • Use of tramadol together with medicines that work on the CNS (such as tranquillizer, hypnotic), can enhance the effect sedasinya.
  • Use of tramadol with tranquillizer can also increase the analgesic effect.


Dose:

  • As with analgesic drugs, the dose should be adjusted according to the severity of pain and clinical response of patients.
  • Dose for adults and children over the age of 14 years:
  • A single dose: 1 capsule.
  • Daily dose: up to 8 capsules.
  • If the pain is still felt, you can add a second single dose of 1 capsule tramadol more, After an interval of 30-60 minutes.
  • In patients with impaired renal and hepatic function, dosage adjustments should be done.


Packaging:

  • Thus the content of 5 strips @ 10 capsules.


Storage:

  • Store in a cool, dry, protected from light.

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